M8189140
Selitrectinib , 98% , 2097002-61-2
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB528.00 | In Stock |
|
| 5mg | RMB1056.00 | In Stock |
|
| 10mg | RMB1728.00 | In Stock |
|
| 25mg | RMB3360.00 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:62.5(Max Conc. mg/mL);164.29(Max Conc. mM) |
| form | A crystalline solid |
| pka | 11.44±0.40(Predicted) |
| color | White to yellow |
| InChI | InChI=1S/C20H21FN6O/c1-12-4-5-16-14(9-13(21)10-22-16)17-3-2-7-26(17)18-6-8-27-19(25-18)15(11-23-27)20(28)24-12/h6,8-12,17H,2-5,7H2,1H3,(H,24,28)/t12-,17-/m1/s1 |
| InChIKey | OEBIHOVSAMBXIB-SJKOYZFVSA-N |
| SMILES | N12CCC[C@]1([H])C1=CC(F)=CN=C1CC[C@@H](C)NC(=O)C1C=NN3C=CC2=NC=13 |
Description and Uses
LOXO-195 (Selitrectinib) is a second-generation TRK kinase inhibitor that targets TRK fusion-positive tumors and is used to treat tumor patients who are resistant to first-generation TRK inhibitors.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
