AR-00341677 , 99% , 905281-76-7

Synonym(s):
1H-Inden-1-one, 2,3-dihydro-5-[1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazol-4-yl]-, oxime;2,3-Dihydro-5-[1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazol-4-yl]-1H-inden-1-one oxime;2-[4-[(1E)-1-(Hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridine-4-yl)-1H-pyrazol-1-yl]ethan-1-ol;5-(1-(2-Hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime

CAS NO.：905281-76-7

Empirical Formula: C19H18N4O2

Molecular Weight: 334.37

MDL number: MFCD16875916

PRODUCT Properties

• Density: 1.37
• storage temp.: Store at -20°C
• solubility: insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL in DMSO
• form: solid
• color: Light yellow to light brown
• Stability: Hygroscopic
• InChI: 1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,24-25H,2,4,9-10H2/b22-18+
• InChIKey: DEZZLWQELQORIU-RELWKKBWSA-N
• SMILES: OCCN(N=C1C2=CC=NC=C2)C=C1C3=CC=C4C(CC/C4=N\O)=C3

Description and Uses

GDC 0879 is a potent B-Raf inhibitor.

Safety

• Symbol(GHS): GHS07
• Signal word: warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
• WGK Germany: WGK 3
• HS Code: 2933399990
• Storage Class: 11 - Combustible Solids