PRODUCT Properties
| Melting point: | 200 °C |
| Boiling point: | 312 °C |
| Density | 1.4062 (rough estimate) |
| refractive index | 1.6100 (estimate) |
| storage temp. | 0-6°C |
| solubility | Acetonitrile (Slightly), DMSO (Sparingly), Metahnol (Slightly) |
| form | Powder |
| pka | 2.75±0.25(Predicted) |
| color | Pale Beige |
| Water Solubility | 700 mg/L (25 ºC) |
| Merck | 13,2082 |
| BRN | 2365906 |
| Exposure limits | An experimental carcinogen. |
| Major Application | peptide synthesis |
| InChI | 1S/C7H5Cl2NO2/c8-3-1-4(7(11)12)6(9)5(10)2-3/h1-2H,10H2,(H,11,12) |
| InChIKey | HSSBORCLYSCBJR-UHFFFAOYSA-N |
| SMILES | Nc1cc(Cl)cc(C(O)=O)c1Cl |
| CAS DataBase Reference | 133-90-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 3-Amino-2,5-dichlorobenzoic acid(133-90-4) |
| EPA Substance Registry System | Chloramben (133-90-4) |
Description and Uses
Chloramben is a colorless, odorless, crystallinesolid. Molecular weight=206.03; Freezing/Meltingpoint=200-201℃; Vapor pressure=6.8 3 1023 mmHg at100℃. Hazard Identification (based on NFPA 704 MRating System): Health 3, Flammability 0, Reactivity 0.Soluble in water; solubility=690 ppm at 25℃.
Chloramben may be used as an analytical reference standard for the determination of the analyte in water samples using liquid chromatography with electrochemical detection (LC-EC).
Safety
| Symbol(GHS) |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315-H319-H335-H350 |
| Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,Xn |
| Risk Statements | 45-36/37/38-40 |
| Safety Statements | 53-22-26-36/37/39-45-36 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | DG1925000 |
| TSCA | TSCA listed |
| HazardClass | 9 |
| HS Code | 29224999 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Carc. 1B Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Hazardous Substances Data | 133-90-4(Hazardous Substances Data) |
| Toxicity | Nontoxic to fish (Hartley and Kidd, 1987); acute oral LD50 for rats 5,620 mg/kg (Hartley and Kidd, 1987), 3,500 mg/kg (RTECS, 1985). |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
