phyproof?ReferenceSubstance , 27409-30-9
Synonym(s):
;6′-Cinnamoylcatalpol
CAS NO.：27409-30-9
Empirical Formula: C24H28O11
Molecular Weight: 492.47
MDL number: MFCD00017720
EINECS: 248-445-1
| Pack Size | Price | Stock | Quantity |
| 20MG | RMB2695.01 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 778.6±60.0 °C(Predicted) |
| Density | 1.56±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble1mg/mL, clear, colorless |
| form | powder |
| pka | 12.70±0.70(Predicted) |
| color | White |
| InChIKey | BSYHSWKTXMTFNF-NTLZGZQOSA-N |
| SMILES | [C@]12(CO)O[C@H]1[C@H]([C@]1([H])C=CO[C@@H](O[C@H]3[C@H](O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@]21[H])OC(=O)/C=C/C1=CC=CC=C1 |&1:0,4,5,6,11,13,14,16,17,19,24,r| |
Description and Uses
Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas. Picroside I is an iridoid glycoside found in picroliv. By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver. Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM. At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.
Picroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P501 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29389090 |
