S-Acetylmercaptosuccinic anhydride , 96% , 6953-60-2

Synonym(s):
2-(Acetylthio)succinic anhydride;SAMSA

CAS NO.：6953-60-2

Empirical Formula: C6H6O4S

Molecular Weight: 174.17

MDL number: MFCD00005526

EINECS: 230-135-2

PRODUCT Properties

• Melting point: 83-86 °C (lit.)
• Boiling point: 354.3±31.0 °C(Predicted)
• Density: 1.42±0.1 g/cm3(Predicted)
• storage temp.: 2-8°C
• Sensitive: Hygroscopic
• InChI: 1S/C6H6O4S/c1-3(7)11-4-2-5(8)10-6(4)9/h4H,2H2,1H3
• InChIKey: AHTFMWCHTGEJHA-UHFFFAOYSA-N
• SMILES: CC(=O)SC1CC(=O)OC1=O
• CAS DataBase Reference: 6953-60-2(CAS DataBase Reference)
• EPA Substance Registry System: Ethanethioic acid, S-(tetrahydro-2,5-dioxo-3-furanyl) ester (6953-60-2)

Description and Uses

S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: TSCA listed
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3