≥95%(LC/MS-UV) , 71950-67-9

CAS NO.：71950-67-9

Empirical Formula:

Molecular Weight:

MDL number:

PRODUCT Properties

• storage temp.: -20°C
• solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble
• form: White to off-white powder.
• Major Application: metabolomics; vitamins, nutraceuticals, and natural products
• InChIKey: UULGWGARYDGVBM-UHFFFAOYSA-N
• SMILES: O=C(C1=C(OC)C(C)=C(OC(C2=C(O)C(C)=C(O)C=C2C)=O)C(C)=C1C)OC3=C(C)C(C)=C(C(O)=O)C(OC)=C3C

Description and Uses

Thielavin B is a fungal metabolite that contains O-substituted salicylic acid. It inhibits cyclooxygenase, blocking both the conversion of arachidonic acid to Prostaglandin H₂ (PGH₂) and the conversion of PGH₂ to PGE₂ (, IC₅₀s = 40 and 9 μM, respectively). Thielavin B also inhibits the reverse transcriptase of avian myeloblastosis virus, bacterial transglycosylases, and telomerase activity.

Thielavin B is a fungal metabolite of?Thielavia terricola that contains O-substituted salicylic acid. It is an inhibitor of viral reverse transcriptase and telomerase.

Safety

• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids