Catecholborane solution , 1.0 MinTHF , 274-07-7

CAS NO.：274-07-7

Empirical Formula: C6H5BO2

Molecular Weight: 119.91

MDL number: MFCD00005846

EINECS: 205-991-5

PRODUCT Properties

• Melting point: 12 °C(lit.)
• Boiling point: 50 °C50 mm Hg(lit.)
• Density: 1.125 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.507(lit.)
• Flash point: 36 °F
• storage temp.: 2-8°C
• solubility: Miscible with diethyl ether, tetrahydrofuran, dichloromethane, chloroform, carbon tetrachloride, toluene, and benzene.
• form: liquid
• color: Hazy Colourless
• Water Solubility: Reacts with water.
• Sensitive: Moisture Sensitive
• BRN: 972072
• Stability: Hygroscopic
• InChIKey: CENMEJUYOOMFFZ-UHFFFAOYSA-N
• CAS DataBase Reference: 274-07-7(CAS DataBase Reference)
• EPA Substance Registry System: 1,3,2-Benzodioxaborole (274-07-7)

Description and Uses

Catecholborane is used to prepare B-alkylcatecholboranes. It finds application for the preparation of amides and macrocyclic lactams from carboxylic acids. It is used as a stereoselective reducing agent to convert beta-hydroxy ketones to syn 1,3-diols. Further, it reacts with alkyne through hydroboration to form trans vinyl borane, which is a precursor to Suzuki reaction.

Safety

• Symbol(GHS): GHS02,GHS05
• Signal word: Danger
• Hazard statements: H225-H314
• Precautionary statements: P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
• Hazard Codes: F,C
• Risk Statements: 11-19-34-67-65-63-48/20-14-40-37
• Safety Statements: 26-36/37/39-45-62-16-43
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 3
• F: 1-10
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• HS Code: 29209090