≥90% , 112137-89-0

CAS NO.：112137-89-0

Empirical Formula: C21H36O5

Molecular Weight: 368.51

MDL number: MFCD07772001

PRODUCT Properties

• Boiling point: 538.3±50.0 °C(Predicted)
• Density: 1.118±0.06 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: Chloroform
• pka: 4.77±0.10(Predicted)
• form: Yellow viscous oil.
• color: Pale Yellow
• Stability: Temperature Sensitive

Description and Uses

Misoprostol is a prostaglandin E₁ analog with agonist activity mediated by EP₂, EP₃, and EP₄ receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED₅₀ = 0.31 μg/kg), inhibit superoxide generation in human neutrophils (EC₅₀ = 0.35 μM), and relax fetal rabbit ductus arteriosus (EC₅₀ = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; ) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.

A cytoprotective prostaglandin PGE1 analogue.

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301-H315-H319-H335-H361
• Precautionary statements: P201-P301+P310+P330-P302+P352-P305+P351+P338
• Hazard Codes: T
• Risk Statements: 45-60-61-25-36/37/38
• Safety Statements: 53-22-36/37/39-45-26
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 2
• HazardClass: 6.1