AvantiPolarLipids900105P,ProstaglandinF1α,powder , 745-62-0

Synonym(s):
Prostaglandin F1α

CAS NO.：745-62-0

Empirical Formula: C20H36O5

Molecular Weight: 356.5

MDL number: MFCD00077862

EINECS: 234-237-8

Pack Size	Price	Stock	Quantity
1mg	RMB534.10	In Stock
others			Enquire

Update time: 2022-07-08

PRODUCT Properties

Melting point:	102.5°C
Boiling point:	409.31°C (rough estimate)
alpha	+24°(D/24℃)(c=0.87,THF)
Density	1.0321 (rough estimate)
refractive index	1.6120 (estimate)
storage temp.	-20°C
solubility	DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 2 mg/ml
form	A crystalline solid
pka	4.78±0.10(Predicted)
color	White to off-white
BRN	2704846
InChI	1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1
InChIKey	DZUXGQBLFALXCR-CDIPTNKSSA-N
SMILES	O[C@@H]1[C@H](CCCCCCC(O)=O)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C1

Description and Uses

Prostaglandin F_1α (PGF_1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF_1α and PGF_2α (Item Nos. 16010 | 10007221) have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10⁻¹¹ M. PGF_1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF_2α. It is only half as active as PGF_2α in inducing human respiratory smooth muscle contractions in vitro.

Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10?11 M. PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro.