(±)-(E)-4-Ethyl-2-(E)-hydroxyimino-5-nitro-3-hexenamide , ≥98% , 138472-01-2

Synonym(s):
NOR-3

CAS NO.：138472-01-2

Empirical Formula: C8H13N3O4

Molecular Weight: 215.21

MDL number: MFCD00270892

PRODUCT Properties

• storage temp.: −20°C
• solubility: DMF: >34 mg/ml; DMSO: >20 mg/ml; Ethanol: >36 mg/ml; PBS pH 7.2: >2.2 mg/ml
• form: White to off-white crystalline solid.
• InChI: 1S/C8H13N3O4/c1-3-6(5(2)11(14)15)4-7(10-13)8(9)12/h4-5,13H,3H2,1-2H3,(H2,9,12)/b6-4+,10-7+
• InChIKey: MZAGXDHQGXUDDX-AGLLBGTNSA-N
• SMILES: CC\C(=C/C(=N\O)C(N)=O)C(C)[N+]([O-])=O

Description and Uses

FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37°C. The IC50 for the inhibition of platelet aggregation is 4.9 μM.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301
• Precautionary statements: P301+P310
• PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• Hazard Codes: T
• Risk Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral