S6180549
≥80%(HPLC),solid , 76343-94-7
Synonym(s):
LAT-B;Latrunculin B, Latrunculia magnifica - CAS 76343-94-7 - Calbiochem
| Pack Size | Price | Stock | Quantity |
| 1mg | RMB2800.88 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| alpha | D24 +112° (c = 0.48 in chloroform) |
| storage temp. | -20°C |
| solubility | DMSO: soluble |
| form | solid |
| color | light yellow |
| optical activity | +120.123 （CHCl3） |
| Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| InChIKey | NSHPHXHGRHSMIK-JRIKCGFMSA-N |
| SMILES | C[C@H]1CC[C@@H]2C[C@H](C[C@@](O)(O2)[C@@H]3CSC(=O)N3)OC(=O)C=C(C)CCC=C1 |
Description and Uses
Latrunculin B (76343-94-7) inhibits actin polymerization and disrupts microfilament organization.1 Significantly more potent than cytochalasins in the disruption of microfilament mediated processes2, causes shortening and thickening of stress fibers. Active in cell culture.3,4Effective doses for latrunculin B vary depending upon cell type but are frequently in the low micromolar range. Note: Latrunculin B is slowly inactivated by fetal bovine serum.
In elucidation of molecular mechanisms of motile processes.
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
