S6288949
purum,≥98.0%(GC) , 532-27-4
Synonym(s):
ω-Chloroacetophenone;Phenacyl chloride
CAS NO.：532-27-4
Empirical Formula: C8H7ClO
Molecular Weight: 154.59
MDL number: MFCD00000933
EINECS: 208-531-1
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 54-56 °C(lit.) |
| Boiling point: | 244-245 °C(lit.) |
| Density | 1.324 g/mL at 25 °C(lit.) |
| vapor pressure | 4 at 20 °C, 14 at 30 °C (quoted, Verschueren, 1983) |
| refractive index | 1.5438 |
| Flash point: | 118°C |
| solubility | Soluble in acetone (Weast, 1986). Freely soluble in alcohol, benzene, and ether (Windholz et al.,
1983) |
| form | Colorless crystals |
| Water Solubility | insoluble. <0.1 g/100 mL at 19 ºC |
| Sensitive | Moisture Sensitive |
| Merck | 14,2115 |
| BRN | 507950 |
| Exposure limits | NIOSH REL: TWA 0.3 mg/m3 (0.05 ppm), IDLH 15 mg/m3; OSHA PEL: TWA
0.05 ppm (0.3 mg/m3); ACGIH TLV: TWA 0.05 ppm (adopted). |
| Stability: | May decompose upon exposure to air or water. Incompatible with bases, amines, alcohols. |
| InChI | 1S/C8H7ClO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2 |
| InChIKey | IMACFCSSMIZSPP-UHFFFAOYSA-N |
| SMILES | ClCC(=O)c1ccccc1 |
| LogP | 1.724 (est) |
| CAS DataBase Reference | 532-27-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Ethanone, 2-chloro-1-phenyl-(532-27-4) |
| EPA Substance Registry System | 2-Chloroacetophenone (532-27-4) |
Description and Uses
Chloroacetophenone is contained in tear gases (lacrimators). This substance has an important irritative potential but can also be a sensitizer.
Chemical warfare agent (CN); principal constituent in riot control agent Mace; in tear gas formulations for personal protection devices
Safety
| Symbol(GHS) |    GHS05,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300-H311+H331-H315-H318-H334-H335 |
| Precautionary statements | P261-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38-42/43-23/25-36-23/24/25 |
| Safety Statements | 22-26-36/37/39-45-28A-7/9 |
| RIDADR | UN 1693 6.1/PG 2 |
| OEB | C |
| OEL | TWA: 0.3 mg/m3 (0.05 ppm) |
| WGK Germany | 3 |
| RTECS | AM6300000 |
| F | 9-19 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | II |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| Hazard Classifications | Acute Tox. 2 Oral Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Eye Dam. 1 Resp. Sens. 1 Skin Irrit. 2 STOT SE 3 |
| Hazardous Substances Data | 532-27-4(Hazardous Substances Data) |
| Toxicity | LD50 in rats (mg/kg): 41 i.v., 36 i.p., 127 orally; LC50 in rats: 8750 mg/min/m3 (Ballantyne, Swanston) |
| IDLA | 15 mg/m3 |
| Excepted Quantities | Not Permitted as Excepted Quantity |
