2,2,2-Trifluoroethanethiol , 95% , 1544-53-2

CAS NO.：1544-53-2

Empirical Formula: C2H3F3S

Molecular Weight: 116.11

MDL number: MFCD00134386

PRODUCT Properties

• Melting point: 51.3-52.3 °C
• Boiling point: 34-35 °C (lit.)
• Density: 1.305 g/mL at 25 °C (lit.)
• vapor pressure: 7.85 psi ( 20 °C)
• refractive index: n20/D 1.352(lit.)
• Flash point: −11 °F
• form: liquid
• pka: 7.60±0.10(Predicted)
• InChI: 1S/C2H3F3S/c3-2(4,5)1-6/h6H,1H2
• InChIKey: RYRLLAOLJVDVNN-UHFFFAOYSA-N
• SMILES: FC(F)(F)CS

Description and Uses

• Advancements in Peptide Synthesis: A novel synthesis of β-thiol phenylalanine showcases the use of 2,2,2-Trifluoroethanethiol in facilitating one-pot ligation-desulfurization chemistry. This technique is pivotal for developing new peptide-based pharmaceuticals, enhancing both the efficiency and versatility of peptide synthesis (Malins et al., 2015).

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H224-H302+H312+H332-H315-H319-H335
• Precautionary statements: P210-P233-P280-P303+P361+P353-P304+P340+P312-P403+P233
• target organs: Respiratory system
• PPE: Eyeshields, Faceshields, Gloves
• Hazard Codes: F+,Xn
• Risk Statements: 12-20/21/22-36/37/38
• Safety Statements: 16-33-38
• RIDADR: UN 3336 3/PG 1
• WGK Germany: 3
• HazardClass: 3.1
• PackingGroup: I
• Storage Class: 3 - Flammable liquids
• Hazard Classifications: Acute Tox. 4 Dermal; Acute Tox. 4 Inhalation; Acute Tox. 4 Oral; Eye Irrit. 2; Flam. Liq. 1; Skin Irrit. 2; STOT SE 3