S656878
Tebbe reagent solution , 0.5 Mintoluene , 67719-69-1
Synonym(s):
Bis(cyclopentadienyl)-μ-chloro-(dimethylaluminum)-μ-methylenetitanium
| Pack Size | Price | Stock | Quantity |
| 25ml | RMB1187.26 | In Stock |
|
| 100ml | RMB2704.64 | In Stock |
|
| 4x25ml | RMB3054.69 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Density | 0.96 g/mL at 20 °C |
| Flash point: | 34 °F |
| storage temp. | Refrigerator |
| form | Solution |
| color | Dark red to purple |
| Water Solubility | Soluble in toluene, benzene, dichloromethane. Insoluble in water. |
| Sensitive | Air & Moisture Sensitive |
| Merck | 9091 |
| Exposure limits | ACGIH: TWA 20 ppm OSHA: Ceiling 300 ppm; TWA 200 ppm NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3) |
| InChI | InChI=1S/2C5.2CH2.C.Al.ClH.Ti/c2*1-2-4-5-3-1;;;;;;/h;;2*1H2;;;1H;/q4*-1;-2;+3;;+4/p-1 |
| InChIKey | QEJAQNUJXFLWSP-UHFFFAOYSA-M |
| SMILES | [CH2-][Al+3]1([Cl-][Ti+4]23456789(C%10[C-]2C3=C4C5=%10)(C2[C-]6C7=C8C9=2)[C-2]1)[CH2-] |
Description and Uses
μ-Chloro-μ-methylenebis(cyclopentadienyl)titaniumdimethylaluminum is used in organic synthesis for carbonyl methylenation, A versatile methylenation reagent for the conversion of ketones and aldehydes to olefins, it offers facile reaction with hindered ketones and allows the conversion of esters to vinyl ethers. Tebbe reagent can be used to olefinate aldehydes, to methylenate a chiral polyhydroxyketone with high diasteroselctivity.
Safety
| Symbol(GHS) |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H261-H302-H318-H333-H361-H225-H304-H314-H336-H361d-H373 |
| Precautionary statements | P223-P301+P310a-P303+P361+P353-P405-P501a-P210-P261-P280-P301+P310-P305+P351+P338-P310 |
| target organs | Central nervous system, Respiratory system |
| PPE | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard Codes | F,C |
| Risk Statements | 11-34-48/20-63-65-67 |
| Safety Statements | 26-36/37/39-45-62-16 |
| RIDADR | UN 2924 3/PG 2 |
| WGK Germany | 2 |
| F | 1-10 |
| HazardClass | 4.3 |
| PackingGroup | II |
| HS Code | 29310099 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Aquatic Chronic 3 Asp. Tox. 1 Eye Dam. 1 Flam. Liq. 2 Repr. 2 Skin Corr. 1B STOT RE 2 STOT SE 3 |
