Home Categories 2-Aminomethyl-18-crown-6
S672578

2-Aminomethyl-18-crown-6 , 95% , 83585-61-9

Synonym(s):
1,4,7,10,13,16-Hexaoxacyclooctadecane-2-methanamine

CAS NO.:83585-61-9

Empirical Formula: C13H27NO6

Molecular Weight: 293.36

MDL number: MFCD00191741

Pack Size Price Stock Quantity
250mg RMB2066.09 In Stock
1g RMB5519.74 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Boiling point: 135 °C/0.08 mmHg (lit.)
Density  1.126 g/mL at 25 °C (lit.)
refractive index  n20/D 1.479(lit.)
Flash point: 113 °C
pka 9.11±0.29(Predicted)
form  liquid
BRN  4184588

Description and Uses

2-Aminomethyl-18-crown-6 (AM-18-C-6) can be used to prepare:

  • AM-18-C-6 bonded Merrifield peptide resin, which is used to study the absorption and the isotopic effect of magnesium.
  • Schiff base of gossypol with aminomethyl crown ether for complexation of monovalent cations.
  • Crown tagged triarylphosphine by reacting with triphenylphosphine carboxylic acid. These tagged triarylphosphine reagents are used in Mitsunobu and Heck reactions for the removal of phosphine derived by-products.
  • 1,16-hexadecanoyl-bis-(2-aminomethyl)-18-crown-6 (bola A-16), which is utilized as a vesicular carrier in a drug delivery system.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3

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