DIF-3 , ≥99%(HPLC),solid , 113411-17-9
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB1107.89 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Boiling point: | 416.9±45.0 °C(Predicted) |
| Density | 1.240±0.06 g/cm3(Predicted) |
| solubility | DMSO: 46 mg/mL, soluble |
| form | solid |
| pka | 5.92±0.45(Predicted) |
| color | White to off-white |
| InChI | 1S/C13H17ClO4/c1-3-4-5-6-8(15)11-9(16)7-10(18-2)12(14)13(11)17/h7,16-17H,3-6H2,1-2H3 |
| InChIKey | JWBMZIJMSBFBIY-UHFFFAOYSA-N |
| SMILES | CCCCCC(=O)c1c(O)cc(OC)c(Cl)c1O |
Description and Uses
DIF-3 has been used: as a glycogen synthase kinase-3β (GSK-3β) activator to determine if GSK-3β is required for the anti-inflammatory actions of VU0360172 (VuPAM) in murine microglia, as a phosphorylation inhibitor for GSK-3β to examine the links between activation of protein kinase B (PKB)/GSK-3β/Fyn axis and nuclear factor erythroid 2–related factor 2 (NRF2) retention, as a GSK3β activator to study its effects on the cyclooxygenase 2 (COX2) expression levels in human primary chondrocytes in response to visfatin, as a GSK3β activator to study its effects on the intracellular mechanics along with F-actin and β-tubulin fiber networks in human primary chondrocytes
Safety
| PPE | Eyeshields, Gloves, type N95 (US) |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
