≥97%(HPLC) , 23583-48-4

Synonym(s):
8-Br-A-3:5-MP;8-Br-cAMP;8-Bromo-cAMP

CAS NO.：23583-48-4

Empirical Formula: C10H11BrN5O6P

Molecular Weight: 408.1

MDL number: MFCD00075580

EINECS: 245-760-6

PRODUCT Properties

• Melting point: 254 °C (dec.) (lit.)
• Boiling point: 741.9±70.0 °C(Predicted)
• Density: 2.80±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: aqueous base: soluble
• form: Powder
• pka: 0.95±0.60(Predicted)
• color: Pale Brown
• Sensitive: Hygroscopic
• BRN: 591930
• InChI: 1S/C10H11BrN5O6P/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(21-9)1-20-23(18,19)22-6/h2-3,5-6,9,17H,1H2,(H,18,19)(H2,12,13,14)/t3-,5-,6-,9-/m1/s1
• InChIKey: DVKQVRZMKBDMDH-UUOKFMHZSA-N
• SMILES: Nc1ncnc2n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c(Br)nc12

Description and Uses

8-Bromoadenosine 3′,5′-cyclic monophosphate has been used:

• to treat H295R cells as positive controls for CYP19 induction
• as a membrane permeable cAMP analog to study its effect on short-circuit current (I_sc)
• to investigate its potential as an inducer of differentiation in Wharton′s jelly-derived mesenchymal stem cells (WJ-MSCs)

Safety

• PPE: Eyeshields, Gloves, type N95 (US)
• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 3-10
• HS Code: 29349990
• Storage Class: 11 - Combustible Solids