S9121914
≥98%(HPLC),solid , 71636-61-8
Synonym(s):
(±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide;(±)-SKF-81297 hydrobromide
CAS NO.：71636-61-8
Empirical Formula: C16H17BrClNO2
Molecular Weight: 370.67
MDL number: MFCD00153782
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB2430.66 | In Stock |
|
| 100mg | RMB7398.01 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| storage temp. | Desiccate at +4°C |
| solubility | H2O: 1.7 mg/mL |
| form | solid |
| color | gray |
| Water Solubility | H2O: 1.7mg/mL DMSO: >10mg/mL ethanol: 6.3mg/mL |
| InChI | 1S/C16H16ClNO2.BrH/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20;/h1-5,8,13,18-20H,6-7,9H2;1H |
| InChIKey | RMIJGBMRNYUZRG-UHFFFAOYSA-N |
| SMILES | Br[H].Oc1cc2C(CNCCc2c(Cl)c1O)c3ccccc3 |
Description and Uses
(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal?regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 22-26-36 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
