Tomatine from Tomato , >80.0%(HPLC) , 17406-45-0
CAS NO.：17406-45-0
Empirical Formula: C50H83NO21
Molecular Weight: 1034.19
MDL number: MFCD00016888
EINECS: 241-429-5
| Pack Size | Price | Stock | Quantity |
| 100mg | RMB1664.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 300-305°C |
| alpha | D20 -18° (c = 0.55 in pyridine) |
| Boiling point: | 806.69°C (rough estimate) |
| Density | 1.48±0.1 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5280 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly) |
| form | Solid |
| pka | 12.77±0.70(Predicted) |
| color | White to Off-White |
| Merck | 14,9545 |
| InChIKey | REJLGAUYTKNVJM-GXOLHJPNNA-N |
| LogP | 2.220 (est) |
| CAS DataBase Reference | 17406-45-0 |
Description and Uses
This glycosidic alkaloid has been obtained from the dried leaves of Lycopersicum pimpinelli/olium (Syn. Solanum racemigerum) and also occurs in L. esculentum; L. hirsutum; L. peruvianum; L. peruvianum var. chutatum and L. putatum. The alkaloid forms colourless needles from MeOH and has a somewhat indefinite melting point about 270°C. It is laevorotatory with [α]20D - 30° (pyridine) and on hydrolysis with H2S04 yields tomatidine, I mole of galactose, 2 moles of glucose and 1 mole of xylose. The tetrasaccharide unit is known as lycotetraose. Partial hydrolysis with acid yields a series of products depending upon which, and how many, of the sugar residues are split off from the molecule. Those which have been isolated are: tomatidine lycotriose I (galactose-glucose-glucose); tomatidine lycotriose II (galactose-glucose-xylose); tomatidine lycobiose (galactose-glucose) and tomatidine-galactose.
Tomatine is used as an antiproliferatice agent used in the suppression of breast adenocarcinoma cells.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| Hazard Codes | Xn |
| Risk Statements | 23/25-22 |
| Safety Statements | 45-24/25-22 |
| RIDADR | 1544 |
| RTECS | XW1050000 |
| HS Code | 29329990 |
| Hazardous Substances Data | 17406-45-0(Hazardous Substances Data) |
| Toxicity | LD orally in rats: 900-1000 mg/kg (Wilson) |
