Coumarin 478 , >98.0%(HPLC) , 41175-45-5
CAS NO.：41175-45-5
Empirical Formula: C18H19NO2
Molecular Weight: 281.35
MDL number: MFCD00041949
EINECS: 255-246-3
| Pack Size | Price | Stock | Quantity |
| 200mg | RMB700.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 149 °C |
| Boiling point: | 538.4±50.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| solubility | DMSO: Slightly soluble: 0.1-1 mg/ml |
| pka | 6.38±0.20(Predicted) |
| form | powder to crystal |
| color | Light orange to Yellow to Green |
| λmax | 375nm(Acetone)(lit.) |
| EPA Substance Registry System | 1H,5H-Cyclopenta[3,4][1]benzopyrano[6,7,8-ij]quinolizin-12(9H)-one, 2,3,6,7,10,11-hexahydro- (41175-45-5) |
Description and Uses
Coumarin 478 is a vital chemical compound used in biomedicine mainly for its anticancer properties. It has demonstrated potential in inhibiting tumor growth and metastasis, making it a valuable drug in the treatment of various types of cancers. Coumarin 478 shows promising results in clinical trials and is actively being researched for its effectiveness against specific cancer types.
Coumarin 106 (Coumarin 478) is a dipolar laser dye. Coumarin 106 is an inhibitor of AChE and BChE. Coumarin 106 displays mixed-type AChE inhibition with a pIC50=4.97 and Ki=2.36 μM. Coumarin 106 inhibits BChE with slightly lower potency (pIC50=4.56)[1][2].
Safety
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-20/21/22 |
| Safety Statements | 37/39-26 |
| HS Code | 29322985 |
