Palmitoyl-L-carnitine Hydrochloride , >98.0%(HPLC) , 18877-64-0
Synonym(s):
O -Palmitoyl-L -carnitine chloride
CAS NO.：18877-64-0
Empirical Formula: C23H46ClNO4
Molecular Weight: 436.07
MDL number: MFCD00070346
EINECS: 242-642-6
| Pack Size | Price | Stock | Quantity |
| 25mg | RMB2052.00 | In Stock |
|
| others | Enquire |
PRODUCT Properties
| Melting point: | 168-172 °C(lit.) |
| storage temp. | -20°C |
| solubility | H2O: 25 mg/mL with heat or sonication |
| form | powder |
| color | white |
| Appearance | white solid |
| Water Solubility | H2O: 25mg/mL (with he at or sonication) |
| BRN | 4071005 |
| InChI | InChI=1/C23H45NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4;/h21H,5-20H2,1-4H3;1H/t21-;/s3 |
| InChIKey | GAMKNLFIHBMGQT-GKNLIIIVNA-N |
| SMILES | [C@@H](CC(=O)O)(C[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC.[Cl-] |&1:0,r| |
| CAS DataBase Reference | 18877-64-0 |
Description and Uses
Hexadecanoylcarnitine, also called as palmitoyl-L-carnitine, is an endogenous acylcarnitine and acts as a key energy donor for β-oxidation. Hexanoylcarnitine chloride is used as an analytical standard in HPLC-MS and MS/MS studies.
Hexanoylcarnitine has surface activity, has a diphilic character and has detergent properties. Hexanoylcarnitine has surface activity, is diphilic and has detergent properties. Hexanoylcarnitine promotes the transfer of long-chain fatty acids from cytoplasm to mitochondria during fatty acid oxidation. The substance accumulates in the myocardium during ischemia and affects the levels of phosphate and free fatty acids in the myocardium and on the myocardial vascular endothelium. In experimental models, palmitoyl-L-carnitine levels increased with age and induced mitochondrial dysfunction in neurons.
Palmitoyl-L-carnitine may be used as an analytical standard to quantify the analyte in biological samples of patients with continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) using HPLC-MS. It may also be used as an analytical reference standard for the separation and identification of underivatized palmitoyl-L-carnitine in human plasma samples.
The product is used primarily as a control for MS/MS.
Palmitoyl-L-carnitine chloride has been used as acylcarnitine in treating cardiomyocytes for the induction of reactive oxygen species (ROS).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 2923900090 |
