1-Acetyl-4-(4-hydroxyphenyl)piperazine , 98% , 67914-60-7

CAS NO.：67914-60-7

Empirical Formula: C12H16N2O2

Molecular Weight: 220.27

MDL number: MFCD00044905

EINECS: 267-744-8

PRODUCT Properties

• Melting point: 180-185 °C (lit.)
• Boiling point: 361.21°C (rough estimate)
• Density: 1.1115 (rough estimate)
• vapor pressure: 0Pa at 20℃
• refractive index: 1.6000 (estimate)
• storage temp.: -20°C Freezer
• solubility: DMSO (Slightly), Methanol (Slightly)
• form: Powder
• pka: 12.18±0.30(Predicted)
• color: White to slightly pink or beige
• Water Solubility: 4.3 g/L (20 ºC)
• BRN: 795777
• InChI: 1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
• InChIKey: AGVNLFCRZULMKK-UHFFFAOYSA-N
• SMILES: CC(=O)N1CCN(CC1)c2ccc(O)cc2
• LogP: 0.3
• CAS DataBase Reference: 67914-60-7(CAS DataBase Reference)

Description and Uses

1-Acetyl-4-(4-hydroxyphenyl)piperazine may be used in the preparation of 1-acetyl-4-(4-octadecyloxyphenyl)piperazine. It may also be used in the multi-step synthesis of ketoconazole, its 1,2,4-triazole and thiazole analogs.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-22
• Safety Statements: 26-36-36/37/39-22
• WGK Germany: 3
• HS Code: 29214910
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3