BD9109431
(cis-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate , 95% , 134071-44-6
CAS NO.：134071-44-6
Empirical Formula: C21H20Cl2N2O5S
Molecular Weight: 483.36
MDL number: MFCD07367827
EINECS: 603-791-6
| Pack Size | Price | Stock | Quantity |
| 5g | RMB69.60 | In Stock |
|
| 10g | RMB109.60 | In Stock |
|
| 25g | RMB226.40 | In Stock |
|
| 100g | RMB604.80 | In Stock |
|
| 500g | RMB1865.60 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 120-122°C |
| Boiling point: | 665.7±55.0 °C(Predicted) |
| Density | 1.44±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 6.88±0.12(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1/C21H20Cl2N2O5S/c1-15-2-5-18(6-3-15)31(26,27)29-12-17-11-28-21(30-17,13-25-9-8-24-14-25)19-7-4-16(22)10-20(19)23/h2-10,14,17H,11-13H2,1H3/t17-,21-/s3 |
| InChIKey | WAXNIYHZFWRPGS-NTMXNBFVNA-N |
| SMILES | [C@@]1(OC[C@@H](COS(=O)(=O)C2C=CC(C)=CC=2)O1)(CN1C=NC=C1)C1=CC=C(Cl)C=C1Cl |&1:0,3,r| |
| CAS DataBase Reference | 134071-44-6(CAS DataBase Reference) |
Description and Uses
cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl p-Tolylsulfonate (Ketoconazole EP Impurity E) is an intermediate in the synthesis of the drug Ketoconazole (K186000).
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P402+P404-P422-P501 |
