D-Arginine , 98% , 157-06-2

Synonym(s):
(R)-2-Amino-5-guanidinopentanoic acid

CAS NO.：157-06-2

Empirical Formula: C6H14N4O2

Molecular Weight: 174.2

MDL number: MFCD00063116

EINECS: 205-866-5

PRODUCT Properties

• Melting point: 226 °C (dec.) (lit.)
• alpha: -28.5 º (c=8, 6 N HCl)
• Boiling point: 305.18°C (rough estimate)
• Density: 1.2297 (rough estimate)
• refractive index: -23 ° (C=8, 6mol/L HCl)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: Aqueous Acid (Slightly), Water (Slightly)
• form: Solid
• pka: 2.49±0.24(Predicted)
• color: White to Off-White
• Water Solubility: SOLUBLE
• Sensitive: Air Sensitive
• BRN: 1725412
• InChIKey: ODKSFYDXXFIFQN-SCSAIBSYSA-N
• LogP: -0.999 (est)
• CAS DataBase Reference: 157-06-2(CAS DataBase Reference)
• EPA Substance Registry System: D-Arginine (157-06-2)

Description and Uses

D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.

1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H319
• Precautionary statements: P264-P280i-P337+P313-P305+P351+P338
• Hazard Codes: Xi,Xn
• Risk Statements: 36-36/37/38-20/21/22
• Safety Statements: 26-36
• WGK Germany: 3
• RTECS: CF1934220
• F: 9
• TSCA: Yes
• HazardClass: IRRITANT
• HS Code: 29252000