(1R,2S)-(+)-cis-1-Amino-2-indanol , 98% , 136030-00-7

Synonym(s):
(1R,2S)-(+)-cis-1-Amino-2-hydroxyindane

CAS NO.：136030-00-7

Empirical Formula: C9H11NO

Molecular Weight: 149.19

MDL number: MFCD00216656

EINECS: 603-940-5

PRODUCT Properties

• Melting point: 118-121 °C(lit.)
• alpha: 44.5 º (c=1, methanol)
• Boiling point: 270.27°C (rough estimate)
• Density: 1.0753 (rough estimate)
• refractive index: 43 ° (C=1, MeOH)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: soluble in Methanol
• pka: 14.79±0.40(Predicted)
• form: Powder
• color: White to light beige
• optical activity: [α]22/D +63°, c = 0.2 in chloroform
• Water Solubility: soluble
• BRN: 2803743
• InChI: InChI=1S/C9H11NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,8-9,11H,5,10H2/t8-,9+/m0/s1
• InChIKey: LOPKSXMQWBYUOI-DTWKUNHWSA-N
• SMILES: [C@@H]1(N)C2=C(C=CC=C2)C[C@@H]1O
• CAS DataBase Reference: 136030-00-7(CAS DataBase Reference)

Description and Uses

This cis-aminoindanol and its antipode have been used in the preparation of a series of potent HIV-1 protease inhibitory peptides. Also, they have served as chiral ligands in the catalytic asymmetric reduction of prochiral ketones with boranes.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• target organs: Respiratory system
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi,Xn
• Risk Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• RIDADR: 2811
• WGK Germany: 3
• F: 10-23
• TSCA: No
• HS Code: 29061990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2; STOT SE 3