A0736712
3-Amino-5-fluoropyridine , 98% , 210169-05-4
Synonym(s):
(5-Fluoropyridin-3-yl)amine;3-Amino-5-fluoropyridine;5-Fluoropyridin-3-amine
CAS NO.：210169-05-4
Empirical Formula: C5H5FN2
Molecular Weight: 112.11
MDL number: MFCD00234073
EINECS: 664-255-5
| Pack Size | Price | Stock | Quantity |
| 1G | RMB36.00 | In Stock |
|
| 5G | RMB172.80 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 86°C |
| Boiling point: | 232.7±20.0 °C(Predicted) |
| Density | 1.257±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| form | powder to crystal |
| pka | 3.74±0.20(Predicted) |
| color | Light orange to Yellow to Green |
| InChI | InChI=1S/C5H5FN2/c6-4-1-5(7)3-8-2-4/h1-3H,7H2 |
| InChIKey | ZRORIJXOWXYPMO-UHFFFAOYSA-N |
| SMILES | C1=NC=C(F)C=C1N |
| CAS DataBase Reference | 210169-05-4(CAS DataBase Reference) |
Description and Uses
3-amino-5-fluoropyridine is an important intermediate mainly used in medicine and organic synthesis. It is used to synthesize Ivosidenib. Ivosidenib is an isocitrate dehydrogenase-1 inhibitor used to treat acute myeloid leukemia and cholangiocarcinoma in adults.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi,Xn |
| Risk Statements | 20/21/22-36/37/38-22 |
| Safety Statements | 26-36-36/37 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
