ProstaglandinH2 , ≥95%，500ug/mlinacetone , 42935-17-1

Synonym(s):
Endoperoxide H₂;PGH₂;Prostaglandin R₂

CAS NO.：42935-17-1

Empirical Formula: C20H32O5

Molecular Weight: 352.47

MDL number: MFCD00036972

EINECS: 200-662-2

PRODUCT Properties

• Boiling point: 490.1±40.0 °C(Predicted)
• Density: 1.129±0.06 g/cm3(Predicted)
• Flash point: -17 °C
• storage temp.: −70°C
• solubility: Ethanol: >100 mg/ml; PBS pH 7.2: >2 mg/ml
• pka: 4.76±0.10(Predicted)
• form: acetone solution
• color: Colorless to light yellow

Description and Uses

Prostaglandin H₂ (PGH₂) was first isolated from incubations of arachidonic acid with ovine seminal vesicle microsomes, and was described as a potent vasoconstrictor. PGH₂ is the precursor for all 2-series PGs and thromboxanes (TXs), and is a TP receptor agonist which irreversibly aggregates human platelets at 50-100 ng/ml.

PGH2 (Prostaglandin H2) is a thromboxane A2 precursor and a platelet aggregator of vascular smooth muscle contraction.

Safety

• Symbol(GHS): GHS02,GHS07
• Signal word: Danger
• Hazard statements: H225-H302+H312+H332-H319
• Precautionary statements: P210-P280-P301+P312-P303+P361+P353-P304+P340+P312-P305+P351+P338
• Hazard Codes: F,Xi
• Risk Statements: 11-36-66-67
• Safety Statements: 9-16-26
• RIDADR: UN 1090 3/PG 2
• WGK Germany: 1