11-deoxyProstaglandinF2α , ≥98% , 37786-06-4

CAS NO.：37786-06-4

Empirical Formula: C20H34O4

Molecular Weight: 338.48

MDL number: MFCD00797656

PRODUCT Properties

• Boiling point: 511.4±45.0 °C(Predicted)
• Density: 1.090±0.06 g/cm3(Predicted)
• storage temp.: Store at -20°C
• solubility: 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a)
• pka: 4.76±0.10(Predicted)

Description and Uses

11-deoxy PGF_2α is a synthetic analog of PGF_2α. It is a more potent agonist than PGF_2α at inducing smooth muscle contractions of rabbit aorta, dog saphenous vein, and guinea pig trachea. It is approximately 20% less potent than U-46619.

11-Deoxyprostaglandin F2α is an activator for TREK-2 channels with EC50 of 0.294 μM. 11-Deoxyprostaglandin F2α inhibits the K2P channel TREK-1[1].

Safety

• Symbol(GHS): GHS02,GHS07,GHS08
• Signal word: Danger
• Hazard statements: H225-H319-H360-H336
• Precautionary statements: P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501