tert-Butyl (S)-2-pyrrolidone-5-carboxylate , 98% , 35418-16-7

Synonym(s):
tert-Butyl (S)-5-oxo-2-pyrrolidinecarboxylate;tert-Butyl L-pyroglutamate;tert-Butyl 5-oxo-L-prolinate

CAS NO.：35418-16-7

Empirical Formula: C9H15NO3

Molecular Weight: 185.22

MDL number: MFCD06659481

EINECS: 252-555-5

PRODUCT Properties

• Melting point: 102.0 to 108.0 °C
• Boiling point: 319.2±35.0 °C(Predicted)
• Density: 1.099±0.06 g/cm3(Predicted)
• storage temp.: Sealed in dry,Room Temperature
• solubility: soluble in Methanol
• pka: 14.65±0.40(Predicted)
• form: Powder
• color: White
• BRN: 3590226
• InChI: 1S/C9H15NO3/c1-9(2,3)13-8(12)6-4-5-7(11)10-6/h6H,4-5H2,1-3H3,(H,10,11)/t6-/m0/s1
• InChIKey: QXGSPAGZWRTTOT-LURJTMIESA-N
• SMILES: CC(C)(C)OC(=O)[C@@H]1CCC(=O)N1

Description and Uses

tert-Butyl (S)-2-pyrrolidone-5-carboxylate can be used:

• As a starting material/synthon in the synthesis of angiotensin-converting enzyme inhibitors.
• In the synthesis of phenanthroindolizidine alkaloids named (+)-tylophorine and antofine.
• As a starting material in the synthesis of radioligands [¹⁸F]IUR-1602 and [¹⁸F]IUR-1601, applicable for imaging of P2X7R, a therapeutic target for neuroinflammation.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319
• Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
• PPE: dust mask type N95 (US), Eyeshields, Gloves
• Hazard Codes: Xi
• Risk Statements: 36/38
• Safety Statements: 26
• WGK Germany: 3
• HS Code: 29339900
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2; Skin Irrit. 2