Home Categories Biochemical Engineering Iniparib (BSI-201)
A1405112

Iniparib (BSI-201) , ≥98% , 160003-66-7

Synonym(s):
4-Iodo-3-nitrobenzamide;BSI-201

CAS NO.:160003-66-7

Empirical Formula: C7H5IN2O3

Molecular Weight: 292.03

MDL number: MFCD11110639

EINECS: 685-396-9

Pack Size Price Stock Quantity
10MG RMB23.20 In Stock
50MG RMB39.20 In Stock
250MG RMB69.60 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 150-153°
Boiling point: 344.8±32.0 °C(Predicted)
Density  2.055±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Store in freezer, under -20°C
solubility  DMSO: soluble5mg/mL, clear
pka 14?+-.0.50(Predicted)
form  powder
color  white to beige
Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Description and Uses

Iniparib (160003-66-7) was originally thought to be a PARP1 inhibitor but this is controversial.1,2?Inhibits ionizing radiation-induced single-stranded DNA break repair in lymphoid cell lines?in vivo.3?Inhibits growth of certain breast cancer cell lines?in vitro. Iniparib non-selectively modifies cysteine-containing proteins in tumor cells.4

Iniparib is an irreversible PARP1 inhibitor. Studies show that potential therapeutic agent for the treatment of cancer, including triple-negative breast cancer.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36-43
Safety Statements  26
WGK Germany  3
HS Code  2921490090

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