A8362512
Veliparib , ≥99% , 912444-00-9
CAS NO.：912444-00-9
Empirical Formula: C13H16N4O
Molecular Weight: 244.29
MDL number: MFCD16661059
EINECS: 681-636-1
| Pack Size | Price | Stock | Quantity |
| 10MG | RMB559.20 | In Stock |
|
| 50MG | RMB1439.20 | In Stock |
|
| 250MG | RMB3199.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 579.0±40.0 °C(Predicted) |
| Density | 1.274 |
| storage temp. | Store at -20°C |
| solubility | insoluble in H2O; ≥10.6 mg/mL in EtOH with ultrasonic; ≥6.11 mg/mL in DMSO |
| form | solid |
| pka | 9.22±0.30(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1 |
| InChIKey | JNAHVYVRKWKWKQ-CYBMUJFWSA-N |
| SMILES | C1([C@@]2(C)CCCN2)NC2=C(C(N)=O)C=CC=C2N=1 |
| CAS DataBase Reference | 912444-00-9 |
Description and Uses
ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo.
Safety
| Symbol(GHS) |   GHS08,GHS07 |
| Signal word | Warning |
| Hazard statements | H341-H373-H361-H302 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P260-P314-P501-P201-P202-P281-P308+P313-P405-P501-P264-P270-P301+P312-P330-P501 |
