1-Benzyl-4-methylpiperidin-3-one hydrochloride , 97% , 1303968-15-1

CAS NO.：1303968-15-1

Empirical Formula: C13H18ClNO

Molecular Weight: 239.75

MDL number: MFCD18914352

PRODUCT Properties

• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Appearance: White to off-white Solid
• InChI: InChI=1S/C13H17NO.ClH/c1-11-7-8-14(10-13(11)15)9-12-5-3-2-4-6-12;/h2-6,11H,7-10H2,1H3;1H
• InChIKey: PZBKCGGUKLHTJJ-UHFFFAOYSA-N
• SMILES: C(C1C=CC=CC=1)N1CCC(C)C(=O)C1.Cl

Description and Uses

1-Benzyl-4-methyl-piperidin-3-one hydrochloride was used for the preparation of key intermediates of tofacitinib. Protein IR89 was utilized to catalyze the generation of (3R, 4R)-1-benzyl-N, 4-dimethylpiperidin-3-amine dihydrochloride from 1-benzyl-4-methylpiperidin-3-one or its hydrochloride and methylamine or its hydrochloride.