A2482812
Calcein, AM , ≥96.0%(HPLC), used for fluorescence analysis , 148504-34-1
Synonym(s):
Calcein O,O′-diacetate tetrakis(acetoxymethyl) ester;Calcein acetoxymethyl ester;Calcein O,O′-diacetate tetrakis(acetoxymethyl) ester;Calcein-acetoxymethyl Ester, Diacetate, CAL-AM;fluorescein complexone
CAS NO.：148504-34-1
Empirical Formula: C46H46N2O23
Molecular Weight: 994.86
MDL number: MFCD00282766
EINECS: 200-664-3
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB1007.20 | In Stock |
|
| 5MG | RMB3519.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | >250℃ |
| Boiling point: | 982.7±65.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| refractive index | n |
| Flash point: | 85 °C |
| storage temp. | -20°C |
| solubility | DMSO: soluble10mg/mL, clear, colorless to slightly yellow |
| pka | 2.66±0.50(Predicted) |
| form | powder |
| color | Colorless |
| Appearance | Solid Powder |
| λmax | < 300 nm |
| Biological Applications | Calcium indicators; zinc indicators; cytotoxicity assays; apoptosis assays; viability assays; labile iron pool assays; chemotaxis probes; cell adhesion probes; mitochondrial probes; P-glycoprotein probes;multi-drug resistance probes;treating atherosclerosis,cancer;ischemic disease |
| InChIKey | BQRGNLJZBFXNCZ-UHFFFAOYSA-N |
| SMILES | C12(C3=C(C=C(OC(C)=O)C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C3)OC3=C1C=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OC(C)=O)=C3)C1=C(C=CC=C1)C(=O)O2 |
Description and Uses
Calcein AM is a non-fluorescent, cell-permeable derivative of calcein, a self-quenching fluorescent dye. Calcein AM can be cleaved to release calcein in cells. Calcein is used as a substrate for multidrug resistance-associated protein 1 (MRP1) and multidrug resistance protein 3 (MDR3, P-glycoprotein 3).
A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule
