Home Categories Pharmaceutical intermediates 2-Chloro-4-methoxypyrimidine
A2521412

2-Chloro-4-methoxypyrimidine , ≥98% , 22536-63-6

CAS NO.:22536-63-6

Empirical Formula: C5H5ClN2O

Molecular Weight: 144.56

MDL number: MFCD00194055

Pack Size Price Stock Quantity
250mg RMB23.20 In Stock
1G RMB31.20 In Stock
5G RMB147.20 In Stock
10g RMB252.80 In Stock
25g RMB419.20 In Stock
100g RMB1290.40 In Stock
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Update time: 2022-07-08

PRODUCT Properties

Melting point: 54-57 °C (lit.)
Boiling point: 96-97 °C(Press: 18 Torr)
Density  1.292±0.06 g/cm3(Predicted)
Flash point: >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
pka 0.07±0.20(Predicted)
form  Crystalline Powder
color  White to yellow
InChI 1S/C5H5ClN2O/c1-9-4-2-3-7-5(6)8-4/h2-3H,1H3
InChIKey BDXYNMVQMBCTDB-UHFFFAOYSA-N
SMILES COc1ccnc(Cl)n1

Description and Uses

2-Chloro-4-methoxypyrimidine is a pharmaceutical intermediate compound used in the preparation of Rilpivirine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of Human Immunodeficiency Virus (HIV) infections, which prevents the replication of the virus.

Safety

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29335990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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