2,4-Dihydroxybenzophenone , 99% , 131-56-6

Synonym(s):
2,4-Dihydroxybenzophenone;BP-1;DHB;EIF4EBP1;PHAS-I

CAS NO.：131-56-6

Empirical Formula: C13H10O3

Molecular Weight: 214.22

MDL number: MFCD00002277

EINECS: 205-029-4

PRODUCT Properties

• Melting point: 144.5-147 °C(lit.)
• Boiling point: 194 °C (1 mmHg)
• Density: 1,32 g/cm³
• bulk density: 750kg/m3
• vapor pressure: 0Pa at 25℃
• refractive index: 1.5090 (estimate)
• Flash point: 125 °C
• storage temp.: Store below +30°C.
• solubility: Chloroform (Slightly, Heated), Ethanol (Slightly, Heated)
• pka: 7.72±0.35(Predicted)
• form: Crystalline Powder
• color: Yellow
• PH: 5 (10g/l, H2O, 20℃)(slurry)
• biological source: human
• Water Solubility: insoluble
• Merck: 14,1106
• BRN: 1311566
• Cosmetics Ingredients Functions: LIGHT STABILIZER; UV ABSORBER
• InChIKey: ZXDDPOHVAMWLBH-UHFFFAOYSA-N
• LogP: 2.964 at 25℃
• CAS DataBase Reference: 131-56-6(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,4-dihydroxyphenyl)phenyl-(131-56-6)
• EPA Substance Registry System: Methanone, (2,4-dihydroxyphenyl)phenyl- (131-56-6)

Description and Uses

2,4-Dihydroxybenzophenone (DHP) is an organic compound derived from Garcinia xanthochymus, but there have been no reports on its biochemical functions and bioavailability. 2,4-dihydroxybenzophenone has been prepared by reacting resorcinol with benzoyl chloride or benzoic acid under anhydrous conditions in the presence of Friedel-Crafts catalysts such as AlCl3 or ZnCl2[1].

Novel mordent and disperse azo dyes were prepared by the coupling of various diazo solutions of aromatic amines with 2, 4-dihydroxybenzophenone. The ultraviolet absorbing monomers were synthesized by reaction of 2, 4-dihydroxybenzophenone with glycidyl acrylate and glycidyl methacrylate. Two new polymerizable stabilizers, 4-benzoyl-2-(α-piperidino-2-chlorobenzyl)-3-hydroxyphenyl acrylate (BPBHA) and corresponding methacrylate (BPBHMA), were synthesized and characterized from 2,4-Dihydroxybenzophenone. a polymerizable UV-stabilizer, 2-hydroxy-4-(3-methacryloxy-2-hydroxylpropoxy) benzophenone (BPMA), was synthesized using 2, 4-dihydroxybenzophenone (UV-0) and glycidyl methacrylate (GMA).

Safety

• Symbol(GHS): GHS07,GHS08,GHS09
• Signal word: Warning
• Hazard statements: H319-H361fd-H411
• Precautionary statements: P202-P264-P273-P280-P305+P351+P338-P308+P313
• Hazard Codes: Xi,T
• Risk Statements: 36-36/37/38-61
• Safety Statements: 26-37/39-45-53
• WGK Germany: 2
• RTECS: DJ0700000
• Hazard Note: Irritant
• TSCA: Yes
• HS Code: 29145000
• Hazardous Substances Data: 131-56-6(Hazardous Substances Data)
• Toxicity: LD50 orally in Rabbit: > 5000 mg/kg