Prunasin , ≥95% , 99-18-3

Synonym(s):
D-Mandelonitrile β-D-glucoside

CAS NO.：99-18-3

Empirical Formula: C14H17NO6

Molecular Weight: 295.29

MDL number: MFCD00049232

EINECS: 202-738-0

PRODUCT Properties

• Melting point: 138-148°C
• Boiling point: 527.0±50.0 °C(Predicted)
• Density: 1.45±0.1 g/cm3(Predicted)
• storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
• form: Powder
• pka: 12.71±0.70(Predicted)
• color: White to off-white
• Stability: Hygroscopic
• InChI: InChI=1/C14H17NO6/c15-6-9(8-4-2-1-3-5-8)20-14-13(19)12(18)11(17)10(7-16)21-14/h1-5,9-14,16-19H,7H2/t9-,10+,11+,12-,13+,14+/s3
• InChIKey: ZKSZEJFBGODIJW-OAWZEMCWNA-N
• SMILES: O([C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@H](C1C=CC=CC=1)C#N |&1:1,2,3,5,7,12,r|

Description and Uses

(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia. It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolase and mandelonitrile lyase and possesses inhibitory effects on plant growth. (R)-Prunasin reportedly inhibits rat DNA polymerase β, which performs base excision repair required for DNA maintenance and replication, with an IC₅₀ value of 98 μM.

Used in the synthesis of cyanogen glycoside. A component of antiperspirants, deodorants, body soaps, shampoos, hair rinses, and hair

Safety

• Symbol(GHS): GHS06,GHS08
• Signal word: Danger
• Hazard statements: H301-H360
• Precautionary statements: P201-P301+P310+P330
• Hazard Codes: T
• Risk Statements: 36/37/38-25-60
• Safety Statements: 26-36/37/39-61-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• RTECS: UL3420000