Di(<i>N</i>-succinimidyl) 3,3'-Dithiodipropionate [Cross-linking Reagent] , >97.0% , 57757-57-0

Synonym(s):
Di(N-succinimidyl) 3,3′-dithiodipropionate;Dithiobis(succinimidyl propionate);DTSP;Lomant’s reagent

CAS NO.：57757-57-0

Empirical Formula: C14H16N2O8S2

Molecular Weight: 404.42

MDL number: MFCD00042045

EINECS: 260-931-5

PRODUCT Properties

• Melting point: 128-133 °C
• Boiling point: 560.1±60.0 °C(Predicted)
• Density: 1.57±0.1 g/cm3(Predicted)
• storage temp.: -20°C
• solubility: chloroform: 50 mg/mL
• form: powder
• color: Off-White
• Appearance: White solid
• BRN: 1518074
• InChI: InChI=1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
• InChIKey: FXYPGCIGRDZWNR-UHFFFAOYSA-N
• SMILES: S(CCC(ON1C(=O)CCC1=O)=O)SCCC(ON1C(=O)CCC1=O)=O
• CAS DataBase Reference: 57757-57-0(CAS DataBase Reference)

Description and Uses

DSP Crosslinker is a cleavable crosslinker. It contains two terminal NHS ester moieties which can react with primary amines. The disulfide bonds can be cleaved via a reduction reaction using Dithiothreitol (DTT) reagent.

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• HS Code: 29309090