Evans Blue , BS , 314-13-6

Synonym(s):
Direct Blue 53

CAS NO.：314-13-6

Empirical Formula: C34H29N6NaO14S4

Molecular Weight: 896.86

MDL number: MFCD00004021

EINECS: 206-242-5

PRODUCT Properties

• storage temp.: Store at RT.
• solubility: DMSO (Slightly), Water (Slightly)
• Colour Index: 23860
• form: Powder/Solid
• color: Dark Brown
• Water Solubility: 280 g/L (20 ºC)
• Merck: 14,3905
• Stability: Stable. Incompatible with strong reducing agents, strong oxidizing agents.
• InChIKey: AFPPOOOTZAGPEB-DVDDBBOFSA-N
• SMILES: NC1=C(C=C(S(O)(=O)=O)C2=CC=C(/N=N/C3C=CC(C4C=CC(/N=N/C5C=CC6=C(C=C(S(O)(=O)=O)C(N)=C6C=5O)S(O)(=O)=O)=C(C)C=4)=CC=3C)C(O)=C12)S(O)(=O)=O.[NaH]
• CAS DataBase Reference: 314-13-6
• IARC: 3 (Vol. 8, Sup 7) 1987
• EPA Substance Registry System: C.I. Direct Blue 53 (314-13-6)

Description and Uses

Evans Blue is used for estimation of blood volume and in double-labeling procedure for studying axonal branching. It acts as an inhibitor of L-glutamate and kainate receptor-mediated currents. It is also a P2X-selective purinoceptor antagonist. It is also useful in molecular biology.

Safety

• Symbol(GHS): GHS08
• Signal word: Danger
• Hazard statements: H350
• Precautionary statements: P201-P202-P280-P308+P313-P405-P501
• Hazard Codes: T,F
• Risk Statements: 45-63-11-61-20/21/22
• Safety Statements: 53-45-36/37-16-36/37/39
• WGK Germany: 3
• RTECS: QJ6440000
• TSCA: Yes
• HS Code: 32129000
• Toxicity: LD50 intraperitoneal in mouse: 340mg/kg