Ethyl α-bromoisobutyrate , 98% , 600-00-0

Synonym(s):
Ethyl 2-bromo-2-methylpropionate

CAS NO.：600-00-0

Empirical Formula: C6H11BrO2

Molecular Weight: 195.05

MDL number: MFCD00000123

EINECS: 209-980-6

Update time: 2022-07-08

PRODUCT Properties

Boiling point:	65-67 °C11 mm Hg(lit.)
Density	1.329 g/mL at 25 °C(lit.)
refractive index	n20/D 1.444(lit.)
Flash point:	140 °F
storage temp.	2-8°C
form	Liquid
color	Clear colorless to light yellow
Water Solubility	Soluble in alcohol, ether. Insoluble in water.
BRN	1098947
Dielectric constant	7.9（20℃）
Stability:	Stable. Incompatible with acids, bases, reducing agents, oxidizing agents.
InChI	InChI=1S/C6H11BrO2/c1-4-9-5(8)6(2,3)7/h4H2,1-3H3
InChIKey	IOLQWGVDEFWYNP-UHFFFAOYSA-N
SMILES	C(OCC)(=O)C(Br)(C)C
CAS DataBase Reference	600-00-0(CAS DataBase Reference)
NIST Chemistry Reference	Propanoic acid, 2-bromo-2-methyl-, ethyl ester(600-00-0)
EPA Substance Registry System	Ethyl 2-bromoisobutyrate (600-00-0)

Description and Uses

Ethyl 2-bromoisobutyrate is an organic compound used in organic synthesis as a catalyst or starting material. The compound has a strong halogen group and can undergo multiple reactions, making it useful in various chemical reactions. One application of this compound is synthesizing cationic polymers for antibacterial peptide mimicry. These polymers showed promising antimicrobial activity against various strains of bacteria.

Ethyl 2-bromoisobutyrate is used as an Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with an ethyl end group.

Safety

Symbol(GHS)	GHS02,GHS05,GHS07
Signal word	Danger
Hazard statements	H226-H302-H318
Precautionary statements	P210-P233-P240-P280-P301+P312-P305+P351+P338
Hazard Codes	Xn
Risk Statements	22-41-36/37/38
Safety Statements	26-39-37/39
RIDADR	UN 1992 3/PG 3
WGK Germany	3
F	19
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29159080
Limited Quantities	5.0 L (1.3 gallons) (liquid)
Excepted Quantities	Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)