2-Fluorobenzyl bromide , 97% , 446-48-0

Synonym(s):
α-Bromo-2-fluorotoluene

CAS NO.：446-48-0

Empirical Formula: C7H6BrF

Molecular Weight: 189.02

MDL number: MFCD00000324

EINECS: 207-169-1

PRODUCT Properties

• Boiling point: 84-85 °C15 mm Hg(lit.)
• Density: 1.567 g/mL at 25 °C(lit.)
• refractive index: n20/D 1.552(lit.)
• Flash point: 181 °F
• storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
• solubility: Chloroform (Slightly), Methanol (Slightly)
• form: Liquid
• Specific Gravity: 1.567
• color: Clear colorless to slightly yellow
• Sensitive: Lachrymatory
• BRN: 1099894
• InChI: InChI=1S/C7H6BrF/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2
• InChIKey: FFWQLZFIMNTUCZ-UHFFFAOYSA-N
• SMILES: C1(CBr)=CC=CC=C1F
• CAS DataBase Reference: 446-48-0(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluorobenzyl bromide(446-48-0)

Description and Uses

2-Fluorobenzyl bromide was used:

• in the synthesis of 2-pyrrolo[2,3-d]pyrimidines
• as alkylating agent during the synthesis of 8-alkylated imidazolo[1,2-a]pyrimid-5-ones
• in the synthesis of prasugrel

Safety

• Symbol(GHS): GHS05,GHS07
• Signal word: Danger
• Hazard statements: H314-H335
• Precautionary statements: P261-P271-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
• Hazard Codes: C
• Risk Statements: 34-36/37
• Safety Statements: 23-26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazard Note: Corrosive/Lachrymatory
• HazardClass: 8
• PackingGroup: III
• HS Code: 29039990
• Limited Quantities: 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid)
• Excepted Quantities: Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)