A4366512
Ferrostatin-1 (Fer-1) , ≥99% , 347174-05-4
| Pack Size | Price | Stock | Quantity |
| 5MG | RMB79.20 | In Stock |
|
| 25MG | RMB239.20 | In Stock |
|
| 100MG | RMB559.20 | In Stock |
|
| 500mg | RMB1599.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 437.3±35.0 °C(Predicted) |
| Density | 1.150±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 4.78±0.11(Predicted) |
| form | powder |
| color | purple to brown |
| Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month. |
| InChI | InChI=1S/C15H22N2O2/c1-2-19-15(18)11-8-9-14(13(16)10-11)17-12-6-4-3-5-7-12/h8-10,12,17H,2-7,16H2,1H3 |
| InChIKey | UJHBVMHOBZBWMX-UHFFFAOYSA-N |
| SMILES | C(OCC)(=O)C1=CC=C(NC2CCCCC2)C(N)=C1 |
Description and Uses
Ferrostatin-1 (347174-05-4) inhibits ferroptosis (EC50=60 nM), an iron-dependent form of nonapoptotic cell death.1?Potent inhibitor of ferroptosis in cancer cells and glutamate-induced cell death in organotypic rat brain slices.1?Blocks the cytotoxic effects of sorafenib in hepatocellular carcinoma cells.2?Ferrostatin-1 inhibits oxidative lipid damage and cell death in diverse disease models3 and prevents apoptosis of renal proximal tubular cells induced by reactive oxygen species4.
Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| HS Code | 2922498590 |
