1-Hydroxy-7-azabenzotriazole , 99% , 39968-33-7

Synonym(s):
3H-[1,2,3]-Triazolo[4,5-b]pyridin-3-ol;HOAt

CAS NO.：39968-33-7

Empirical Formula: C5H4N4O

Molecular Weight: 136.11

MDL number: MFCD00210053

EINECS: 609-760-3

PRODUCT Properties

• Melting point: 213-216°C
• Boiling point: 250.36°C (rough estimate)
• Density: 0.973 g/mL at 20 °C
• refractive index: n20/D 1.441
• Flash point: 213-216°C
• storage temp.: Store at RT.
• solubility: >6.8mg/mL in DMSO
• form: Powder
• pka: 5.85±0.58(Predicted)
• color: White to yellow
• Decomposition: 213-216 ºC
• InChI: InChI=1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H
• InChIKey: FPIRBHDGWMWJEP-UHFFFAOYSA-N
• SMILES: C12N(O)N=NC1=CC=CN=2
• CAS DataBase Reference: 39968-33-7(CAS DataBase Reference)
• EPA Substance Registry System: 3H-1,2,3-Triazolo[4,5-b]pyridine, 3-hydroxy- (39968-33-7)

Description and Uses

HOAt (also known as 1-Hydroxy-7-azabenzotriazole) is a benzotriazole compound commonly used as a coupling reagent for amino acids and peptides. HOAt is also used as a solid-phase synthesis reagent for chiral peptide nucleic acids.

1-Hydroxy-7-azabenzotriazole can be used as antibacterial, anti-aging and flame-retardant dendritic polyacrylate emulsion.

Safety

• Symbol(GHS): GHS01,GHS07
• Signal word: Warning
• Hazard statements: H302-H204-H319-H315
• Precautionary statements: P264-P270-P301+P312-P330-P501-P210-P240-P250-P280-P370+P380-P372-P373-P374-P401-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
• Hazard Codes: T,Xi,F,Xn,E
• Risk Statements: 61-20/21-36-5-36/37/38-11-41-37/38-22-2-36/37
• Safety Statements: 53-45-37/39-26-16-39-35-36-36/37-28-15
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 1
• HazardClass: IRRITANT
• PackingGroup: Ⅱ
• HS Code: 29332990