(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine , 97% , 110529-22-1

Synonym(s):
(S)-α,α-Diphenyl-N-methyl-2-pyrrolidinemethanol

CAS NO.：110529-22-1

Empirical Formula: C18H21NO

Molecular Weight: 267.37

MDL number: MFCD00145245

EINECS: 634-571-8

PRODUCT Properties

• Melting point: 66-72 °C
• alpha: +52° (c=1, CHCl3)
• Boiling point: 406.8±25.0 °C(Predicted)
• Density: 1.116±0.06 g/cm3(Predicted)
• refractive index: 55 ° (C=1, CHCl3)
• storage temp.: Sealed in dry,2-8°C
• solubility: sol hexane, benzene, toluene, Et2O, cyclohexane, dichloromethane
• pka: 13.15±0.29(Predicted)
• form: Powder
• color: white to pale-yellow
• optical activity: [α]20/D +55±3°, c = 1% in chloroform stab. with amylenes
• BRN: 4749387
• CAS DataBase Reference: 110529-22-1(CAS DataBase Reference)

Description and Uses

(S)-(+)-2-[Hydroxy(diphenyl)methyl]-1-methylpyrrolidine is used for chiral ligand for the enantioselective addition of dialkylzincs, alkynylzinc, and cyanomethylzinc bromide to aldehydes; chiral ligand for the enantioselective Reformatsky reaction; chiral ligand for the enantioselective Diels-Alder reaction; chiral auxiliary for asymmetric polymerization.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-34
• HS Code: 29339900