Indole-6-carboxylic Acid , 98% , 1670-82-2

Synonym(s):
6-Carboxyindole

CAS NO.：1670-82-2

Empirical Formula: C9H7NO2

Molecular Weight: 161.16

MDL number: MFCD02258929

EINECS: 605-464-3

PRODUCT Properties

• Melting point: 249-253 °C(lit.)
• Boiling point: 287.44°C (rough estimate)
• Density: 1.2480 (rough estimate)
• refractive index: 1.5050 (estimate)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• pka: 4.44±0.30(Predicted)
• form: Powder
• color: Yellow-beige to orange-brown
• BRN: 123991
• InChI: InChI=1S/C9H7NO2/c11-9(12)7-2-1-6-3-4-10-8(6)5-7/h1-5,10H,(H,11,12)
• InChIKey: GHTDODSYDCPOCW-UHFFFAOYSA-N
• SMILES: N1C2=C(C=CC(C(O)=O)=C2)C=C1
• CAS DataBase Reference: 1670-82-2(CAS DataBase Reference)

Description and Uses

• Reactant for preparation of D-glutamic acid-based inhibitors of E. coli MurD ligase
• Reactant for preparation of indolylindazoles and indolylpyrazolopyridines as interleukin-2 inducible T cell kinase inhibitors
• Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway
• Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity
• Reactant for preparation of pyridinyl carboxylates via esterification with chlorohydroxypyridine as SARS-CoV 3CL proinhibitors
• Reactant for preparation of (indolecarbonyl)-D-phenylglycinamide amides as factor Xa inhibitors

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a
• Hazard Codes: Xn,Xi
• Risk Statements: 36/37/38-21/22-20/21/22-51-36-22
• Safety Statements: 22-24/25-37/39-26
• WGK Germany: 3
• Hazard Note: Irritant
• HS Code: 29339900