(2<i>S</i>,4<i>S</i>)-1-(<i>tert</i>-Butoxycarbonyl)-4-fluoro-2- pyrrolidinecarboxylic Acid , ≥97.0% , 203866-13-1

CAS NO.：203866-13-1

Empirical Formula: C10H16FNO4

Molecular Weight: 233.24

MDL number: MFCD04973957

PRODUCT Properties

• Melting point: 157-161.°C
• Boiling point: 346.0±42.0 °C(Predicted)
• Density: 1.24±0.1 g/cm3(Predicted)
• refractive index: -57 ° (C=1, MeOH)
• storage temp.: Keep in dark place,Sealed in dry,Room Temperature
• form: powder to crystal
• pka: 3.53±0.40(Predicted)
• color: White to Almost white
• optical activity: [α]22/D 71.0±5°, c = 1 in chloroform
• InChI: InChI=1S/C10H16FNO4/c1-10(2,3)16-9(15)12-5-6(11)4-7(12)8(13)14/h6-7H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m0/s1
• InChIKey: YGWZXQOYEBWUTH-BQBZGAKWSA-N
• SMILES: N1(C(OC(C)(C)C)=O)C[C@@H](F)C[C@H]1C(O)=O
• CAS DataBase Reference: 203866-13-1(CAS DataBase Reference)

Description and Uses

N-Boc-cis-4-fluoro-L-proline can be used as a substrate in the preparation of:

• α4β2 Receptor ligands bearing pyrrolidine nucleus.
• β-Amino pyrrolidine-2-carbonitrile derivatives as possible dipeptidyl peptidase IV (DPP4) inhibitors.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H315-H319-H335
• Precautionary statements: P261-P264-P271-P280-P302+P352-P305+P351+P338
• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 29339900