(+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] , 96% , 150529-93-4

Synonym(s):
(R,R)-2,2′-Bis(4-phenyl-2-oxazolin-2-yl)propane;(R,R)-2,2′-Isopropylidenebis(4-phenyl-2-oxazoline)

CAS NO.：150529-93-4

Empirical Formula: C21H22N2O2

Molecular Weight: 334.41

MDL number: MFCD00192244

PRODUCT Properties

• Melting point: 56-58 °C(lit.)
• Boiling point: 468.9±45.0 °C(Predicted)
• Density: 1.18±0.1 g/cm3(Predicted)
• refractive index: 160 ° (C=1, EtOH)
• storage temp.: -20°C
• form: clear liquid
• pka: 4.85±0.70(Predicted)
• color: Light yellow to Amber to Dark green
• optical activity: [α]20/D +160°, c = 1 in ethanol
• BRN: 4266906
• InChI: 1S/C21H22N2O2/c1-21(2,19-22-17(13-24-19)15-9-5-3-6-10-15)20-23-18(14-25-20)16-11-7-4-8-12-16/h3-12,17-18H,13-14H2,1-2H3/t17-,18-/m0/s1
• InChIKey: JTNVCJCSECAMLD-ROUUACIJSA-N
• SMILES: CC(C)(C1=N[C@@H](CO1)c2ccccc2)C3=N[C@@H](CO3)c4ccccc4
• CAS DataBase Reference: 150529-93-4

Description and Uses

(+)-2,2′-Isopropylidenebis[(4R)-4-phenyl-2-oxazoline] in the presence of copper iodide, can catalyze the asymmetric cyclopropanation reaction of phenyliodonium ylides with alkenes to form cyclopropane α-amino acid esters.

Safety

• Symbol(GHS): GHS06
• Signal word: Danger
• Hazard statements: H301+H311+H331
• Precautionary statements: P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
• PPE: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• Hazard Codes: T
• Risk Statements: 23/24/25
• Safety Statements: 26-36-45
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• HS Code: 29349990
• Storage Class: 6.1C - Combustible acute toxic Cat.3; toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Dermal; Acute Tox. 3 Inhalation; Acute Tox. 3 Oral