A5654912
Methyl Diethylphosphonoacetate , >96.0%(GC) , 1067-74-9
Synonym(s):
(Methoxycarbonylmethyl) diethoxyphosphine oxide;[(Methoxycarbonyl)methyl]phosphonic acid diethyl ester;Methyl P,P-diethylphosphonoacetate;NSC 147757
CAS NO.：1067-74-9
Empirical Formula: C7H15O5P
Molecular Weight: 210.16
MDL number: MFCD00009081
EINECS: 213-938-2
| Pack Size | Price | Stock | Quantity |
| 5G | RMB25.60 | In Stock |
|
| 25G | RMB37.60 | In Stock |
|
| 100G | RMB105.60 | In Stock |
|
| 500G | RMB502.40 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Boiling point: | 127-131 °C9 mm Hg(lit.) |
| Density | 1.145 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Miscible with tetrahydrofuran. |
| form | Liquid |
| color | Clear colorless to faint yellow |
| BRN | 1782397 |
| InChI | InChI=1S/C7H15O5P/c1-4-11-13(9,12-5-2)6-7(8)10-3/h4-6H2,1-3H3 |
| InChIKey | CTSAXXHOGZNKJR-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)CP(OCC)(OCC)=O |
| CAS DataBase Reference | 1067-74-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Acetic acid, phosphono-, p,p-diethyl c-methyl ester(1067-74-9) |
Description and Uses
Methyl diethylphosphonoacetate is used as a reagent in the preparation of allylic fluorides compounds and in regioselective Diels-Alder reactions. It also serves as a reactant in the preparation of substituted thiophenes and furans, which finds application in type 2 diabetes treatment. Further, it acts as a precursor in the synthesis of pyridone alkaloids and immunosuppressive cyclopentanediol derivatives. In addition to this, it is utilized in the modification of botulinum neurotoxin serotype A protease inhibitors.
