1-Naphthohydroxamic Acid , >98.0% , 6953-61-3

Synonym(s):
1-Naphthohydroxamic Acid, N-Hydroxynaphthalene-1-carboxamide, Histone Deacetylase Inhibitor XIX;a-Naphthohydroxamic acid;HDAC Inhibitor XIX, Compound 2 - CAS 6953-61-3 - Calbiochem;N-Hydroxynaphthalene-1-carboxamide;NSC 57457

CAS NO.：6953-61-3

Empirical Formula: C11H9NO2

Molecular Weight: 187.19

MDL number: MFCD00059546

PRODUCT Properties

• Melting point: 176-178 °C
• Density: 1.291±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: ≥5mg/mL
• form: White solid
• pka: 8.91±0.30(Predicted)
• color: white to tan
• InChI: 1S/C11H9NO2/c13-11(12-14)10-7-3-5-8-4-1-2-6-9(8)10/h1-7,14H,(H,12,13)
• InChIKey: JRZGPWOEHDOVMC-UHFFFAOYSA-N
• SMILES: ONC(=O)c1cccc2ccccc12

Description and Uses

1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6.

Safety

• Symbol(GHS): GHS07
• Signal word: Warning
• Hazard statements: H312-H302-H332
• Precautionary statements: P280-P302+P352-P312-P322-P363-P501-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312
• Risk Statements: 52
• WGK Germany: 3
• RTECS: QJ1894500
• HS Code: 2928009090
• Storage Class: 11 - Combustible Solids