A6791312
PF-04691502 , 98% , 1013101-36-4
Synonym(s):
2-Amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxy-3-pyridinyl)-4-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one;PF04691502;PF-4691502
CAS NO.：1013101-36-4
Empirical Formula: C22H27N5O4
Molecular Weight: 425.48
MDL number: MFCD18782794
| Pack Size | Price | Stock | Quantity |
| 1MG | RMB277.60 | In Stock |
|
| 5MG | RMB503.20 | In Stock |
|
| 10MG | RMB719.20 | In Stock |
|
| 50MG | RMB1999.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 219-221°C |
| Boiling point: | 682.5±65.0 °C(Predicted) |
| Density | 1.36 |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly, Heated, Sonicated), Methanol (Slightly, Sonicated) |
| form | Solid |
| pka | 14.39±0.10(Predicted) |
| color | Pale Yellow to Light Green |
| InChIKey | XDLYKKIQACFMJG-WKILWMFISA-N |
| SMILES | C1(N)=NC(C)=C2C=C(C3=CC=C(OC)N=C3)C(=O)N([C@@H]3CC[C@@H](OCCO)CC3)C2=N1 |
Description and Uses
PF-04691502 is an ATP-competitive PI3K/mTOR inhibitor with IC50 of 32 nM and also inhibits Akt T308/S473 with IC50 of 7.5 nM/3.8 nM.
