A6847112
Phthalazone , ≥98.0% , 119-39-1
Synonym(s):
Benzo[d]pyridazin-1(2H)one
CAS NO.：119-39-1
Empirical Formula: C8H6N2O
Molecular Weight: 146.15
MDL number: MFCD00006892
EINECS: 204-319-8
| Pack Size | Price | Stock | Quantity |
| 25G | RMB63.20 | In Stock |
|
| 100G | RMB191.20 | In Stock |
|
| 500G | RMB767.20 | In Stock |
|
| others | Enquire |
Update time: 2022-07-08
PRODUCT Properties
| Melting point: | 183-185 °C(lit.) |
| Boiling point: | 337°C(lit.) |
| Density | 1.2312 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 12.29±0.20(Predicted) |
| form | Crystalline Powder |
| color | Off-white to pale yellow |
| BRN | 3654 |
| InChI | InChI=1S/C8H6N2O/c11-8-7-4-2-1-3-6(7)5-9-10-8/h1-5H,(H,10,11) |
| InChIKey | IJAPPYDYQCXOEF-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2)C=NN1 |
| CAS DataBase Reference | 119-39-1(CAS DataBase Reference) |
| EPA Substance Registry System | 1(2H)-Phthalazinone (119-39-1) |
Description and Uses
Phthalazone is a remarkable scaffold in drug discovery. Also, functions as an oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
Safety
| Symbol(GHS) |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
| Hazard Codes | Xn |
| Risk Statements | 22-68-36/37/38 |
| Safety Statements | 22-24/25-36/37/39-26 |
| WGK Germany | 3 |
| RTECS | TH9185000 |
| HazardClass | IRRITANT |
| HS Code | 29339990 |
| Hazardous Substances Data | 119-39-1(Hazardous Substances Data) |
| Toxicity | mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00139, |
